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Table 2 Unadjusted and risk-adjusted associations of patient preoperative comorbidities and PLOS (n = 4,495,582)

From: Association between postoperative complications and hospital length of stay: a large-scale observational study of 4,495,582 patients in the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) registry

Patient Comorbidities

N (%)

Unadjusted Median LOS (IQR)*

Risk-Adjusted Median LOS (IQR)*^

Risk-Adjusted Change in LOS (days)

Ascites

 No

4,463,494 (99.3)

3 (1–5)

3.0 (2.4–4.7)

Reference

 Yes

32,088 (0.7)

7 (4–13)

8.1 (4.6–15.2)

 + 5.1

Bleeding Disorder

 No

4,221,545 (93.9)

3 (1–5)

3.0 (2.3–4.5)

Reference

 Yes

274,037 (6.1)

4 (2–8)

4.7 (3.1–7.8)

 + 1.7

Congestive Heart Failure

 No

4,442,958 (98.8)

3 (1–5)

3.0 (2.4–4.7)

Reference

 Yes

52,624 (1.2)

6 (3–11)

6.8 (4.2–11.7)

 + 3.8

Chronic Obstructive Pulmonary Disease

 No

4,238,804 (94.3)

3 (1–5)

3.0 (2.3–4.6)

Reference

 Yes

256,778 (5.7)

4 (2–8)

4.4 (3.1–7.3)

 + 1.4

Diabetes

 None

3,686,880 (82.0)

3 (1–5)

2.9 (2.3–4.5)

Reference

 Oral

488,422 (10.9)

3 (2–5)

3.2 (2.6–5.0)

 + 0.3

 Insulin

320,280 (7.1)

4 (2–7)

4.3 (3.0–7.3)

 + 1.4

Dialysis Within 2 Weeks

 No

4,419,883 (98.3)

3 (1–5)

3.0 (2.4–4.6)

Reference

 Yes

75,699 (1.7)

5 (3–10)

6.5 (4.0–11.0)

 + 3.5

Disseminated Cancer

 No

4,346,644 (96.7)

3 (1–5)

3.0 (2.3–4.5)

Reference

 Yes

148,938 (3.3)

5 (3–9)

5.8 (4.3–8.5)

 + 2.8

Dyspnea

 None

4,132,503 (91.9)

3 (1–5)

3.0 (2.3–4.6)

Reference

 Moderate Exertion

324,162 (7.2)

3 (2–6)

3.5 (2.7–5.9)

 + 0.5

 At Rest

38,917 (0.9)

6 (3–12)

6.8 (3.9–13.4)

 + 3.8

Hypertension

 No

2,185,001 (48.6)

2 (1–5)

2.7 (2.2–4.2)

Reference

 Yes

2,310,581 (51.4)

3 (2–6)

3.3 (2.6–5.2)

 + 0.6

Acute Renal Failure

 No

4,470,065 (99.4)

3 (1–5)

3.0 (2.4–4.7)

Reference

 Yes

25,517 (0.6)

7 (3–15)

9.1 (5.0–17.2)

 + 6.1

Body Mass Index

 Null/unknown

116,741 (2.6)

3 (1–7)

4.1 (2.6–7.1)

 + 0.6

 Underweight (< 18.5)

93,640 (2.1)

5 (2–8)

5.3 (3.2–8.3)

 + 1.8

 Normal weight (18.5–24.9)

1,046,902 (23.3)

3 (2–6)

3.5 (2.4–5.7)

Reference

 Overweight (25.0–29.9)

1,316,392 (29.3)

3 (1–5)

3.0 (2.3–4.7)

-0.5

 Obese Class I (30.0–34.9)

907,049 (20.2)

3 (1–5)

2.9 (2.3–4.2)

-0.6

 Obese Class II (35.0–39.9)

495,640 (11.0)

3 (1–4)

2.8 (2.3–2.8)

-0.7

 Obese Class III (≥ 40)

519,218 (11.6)

2 (1–4)

2.7 (2.4–3.3)

-0.8

Chronic Steroid Use

 No

4,296,364 (95.6)

3 (1–5)

3.0 (2.3–4.6)

Reference

 Yes

199,218 (4.4)

4 (2–7)

4.3 (3.1–6.9)

 + 1.3

Transfusion of > 4 pRBC Within 72 Hours

 No

4,432,967 (98.6)

3 (1–5)

3.0 (2.4–4.6)

Reference

 Yes

62,615 (1.4)

7 (4–13)

8.0 (5.1–13.7)

 + 5.0

Ventilator Dependent within 48 h

 No

4,464,439 (99.3)

3 (1–5)

3.0 (2.4–4.7)

Reference

 Yes

31,143 (0.7)

13 (5–23)

15.4 (8.8–28.5)

 + 12.4

Open Wound With or Without Infection

 No

4,291,538 (95.5)

3 (1–5)

3.0 (2.3–4.4)

Reference

 Yes

204,044 (4.5)

6 (3–10)

7.1 (4.9–10.8)

 + 4.1

Weight Loss > 10% Within 6 Months

 No

4,399,721 (97.9)

3 (1–5)

3.0 (2.3–4.6)

Reference

 Yes

95,861 (2.1)

6 (4–10)

7.1 (4.7–11.0)

 + 4.1

Systemic Sepsis (Within 48 Hours)

 None

4,107,362 (91.4)

3 (1–5)

2.9 (2.3–4.4)

Reference

 Systemic Inflammatory Response Syndrome

209,239 (4.7)

4 (2–8)

4.2 (2.5–7.9)

 + 1.3

 Sepsis

144,660 (3.2)

6 (3–11)

7.4 (3.9–13.3)

 + 4.5

 Septic Shock

34,321 (0.8)

12 (5–21)

14.2 (8.4–25.7)

 + 11.3

  1. Abbreviation: IQR Interquartile range, LOS Length of stay, pRBC packed Red Blood Cells
  2. ^ Risk-adjustment was accomplished using a negative binomial model with PLOS as the dependent variable and the preoperative variables and postoperative complications as the independent variables
  3. * All p values were < 0.0001