Skip to main content
Fig. 2 | Patient Safety in Surgery

Fig. 2

From: Lessons learned from the mechanisms of posttraumatic inflammation extrapolated to the inflammatory response in COVID-19: a review

Fig. 2

Proposed model of consecutive insult conditions and systemic inflammatory disease progression in COVID-19, based on established trauma modelling. Established concepts in the field of severe trauma and related inflammatory complications have been applied to COVID-19 disease progression. Systemic inflammation may contribute to the restoration of homeostasis and should be considered a physiological process. However, altered inflammatory response may lead to hyperinflammation or a pathological hypo-inflammatory immune response. See text for details and explanations. Abbreviations: SIRS, systemic inflammatory response syndrome; CARS, compensatory anti-inflammatory response syndrome

Back to article page

Patient Safety in Surgery

ISSN: 1754-9493